Faculty & Staff

MARIA C NAGAN

PROFESSOR

CHEMISTRY

SCIENCE BUILDING
ROOM 202

p - 516-877-4138

f - 516-877-4485

e - MNAGAN@ADELPHI.EDU

w - http://jade.adelphi.edu/labwiki

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Diplomas/Degrees

Ph.D. Chemistry, University of Minnesota-Twin Cities (2001)
B.A. Chemistry, Grinnell College (1997)

Recent Courses

General Chemistry I
Physical Chemistry I
Physical Chemistry II
Physical Chemistry Lab I
Undergraduate Research In Chemistry I
Undergraduate Research In Chemistry II

Teaching Specializations/Interests

General Chemistry, Physical Chemistry, Biochemistry

Research Interests

Computational studies examining thermodynamics of RNA structure and protein recognition of RNA

Grants/Sponsored Research

NASA-Missouri Space Grant Consortium, verbally approved, needs final Board approval, 4/1/13-9/30/15 "Continuing the Multidisciplinary Astrobiology Research Community at Truman State Univ." $22,000 served as co-PI until 8/13; Eric Patterson– PI.

National Science Foundation – Major Research Instrumentation, 9/1/12-8/31/15 “MRI: Acquisition of High Performance Computers for the Molecular Education and Research Consortium in Undergraduate computational chemistRY (MERCURY)", $200,000, serving as Senior Personnel, George Shields – PI, CHE-1229354.

NASA-Missouri Space Grant Consortium, 4/1/12-9/30/14 "Expanding the Multidisciplinary Astrobiology Research Community at Truman State Univ." $20,000 serving as co-PI; Eric Patterson– PI.

National Science Foundation, Educational Grant - Teragrid, 1/1/11-1/1/12 " Computational Studies of Peptide-RNA Complexes: Hands-On Learning in a Senior-Level Biochemistry Course", 100,000 service units, TG- MCB110049.

NASA-Missouri Space Grant Consortium, 4/1/11-9/30/11 "Strengthening the Multidisciplinary Astrobiology Research Community at Truman State Univ." $26,514, serving as co-PI; Matthew Beaky – PI.

National Science Foundation – Major Research Instrumentation, 6/1/08-5/31/11 “MRI: Acquisition of a High Performance Computer for the Molecular Education and Research Consortium in Undergraduate computational chemistRY (MERCURY)", $229,000, serving as Senior Personnel, George Shields – PI, CHE-0821581.

National Science Foundation - Research in Undergraduate Institutions, 2/1/08-1/31/12 “RUI: Quantum Characterization of Stair-Stepped Base Stacking Interactions in tRNA”, $158,033, serving as co-PI; Eric V. Patterson – PI, CHE-074096.

NASA-Missouri Space Grant Consortium, 10/1/09-4/30/10 "Establishing a Multidisciplinary Astrobiology Research Community at Truman State Univ." $32,747, serving as co-PI; Matthew Beaky – PI.

National Science Foundation, STEP-Type I “The Next STEP: Integrating STEM Learning Communities” 9/04-9/09, $1,992,958, served as co-PI 03/06-09/07. Jason Miller – PI; Jeffrey Osborn - original PI, DUE-0431664.

Cottrell College Science Award, Research Corporation, 6/15/06-6/15/08 “Molecular Dynamics Studies of Human Immunodeficiency Virus Rev-RRE Recognition” $35,400, CC6553.

National Science Foundation, Medium Resource Allocation - Teragrid, 9/06-12/07 "Molecular Dynamics Studies of Ribonucleic Acid Structure and Function", 101,760 service units, TG-CHE070021N.

Petroleum Research Fund Type G, 9/1/04-8/31/07, “Molecular Dynamics Analyses of Posttrascriptionally Modified tRNA Molecules” $35,000, 41701-GB7.

National Science Foundation, Development Allocation - Teragrid, 9/1/05-9/1/06 "Molecular Dynamics Studies of RNA Recognition", 30,000 service units, TG-CHE050078T.

National Science Foundation – Major Research Instrumentation, 9/1/05 “Acquisition of a Linux Cluster for the Molecular Education and Research Consortium in Undergraduate computational chemistRY (MERCURY)" $100,000, George Shields – PI, CHE- 0521063.

Refereed Articles

Witts, R.N.; Hopson, E.C.; Koballa, D.E.; Van Boening, T.A.; Hopkins, N.H.; Patterson, E.V. and Nagan, M.C. (2013), Backbone-Base Interactions Critical to Quantum Stabilization of Transfer RNA Anticodon Structure. J. Phys. Chem. B, 117, 7489-7497.

Michael, L.A.; Chenault, J.A.; Miller III, B.R.; Knolhoff, A.M. and Nagan, M.C. (2009), Water, Shape-Recognition, Salt Bridges and Pi-Cation Interactions Differentiate Peptide Recognition of the HIV Rev-Responsive Element. J. Mol. Biol., 392, 774-786.

Hati, S.; Ziervogel, B.; SternJohn, J.; Wong, F.-C.; Nagan, M.C.; Rosen, A.E.; Siliciano, P.G.; Chihade, J.W. and Musier-Forsyth, K. (2006), Pre-transfer Editing by Class II Prolyl-tRNA Synthetase: Role of Aminoacylation Active Site in "Selective Release" of Noncognate Amino Acids. J. Biol. Chem., 281, 27862-27872.

McCrate, N.E.; Varner, M.E.; Kim, K.I. and Nagan, M.C. (2006), Molecular Dynamics Simulations of Human tRNALys,3UUU: The Role of Modified Bases in mRNA Recognition. Nucleic Acids Res., 34, 5361-5368.

Polaske, N.W.; Wood, A.L.; Campbell, M.R.; Nagan, M.C. and Pollak, L.M. (2005), Amylose Determination of Native High-Amylose Corn Starches by Differential Scanning Calorimetry. Starch, 57, 118-123.


Invited Presentation/Lecture

Maria Nagan (2015, November). Computational Chemistry and What You Can Do with It. Iona College, New Rochelle, NY.

Maria Nagan (2015, March). The Role of Water in Arginine-Rich Motif Peptide-RNA Recognition. American Chemical Society, Denver, CO.

Maria Nagan (2015, March). The Role of Water in Peptide-RNA Recognition. CUNY-Lehman College, NY.

Maria Nagan (2014, April). The Role of Modified Bases in Transfer RNA Structure. Iowa State University, Ames, IA.

Maria Nagan (2011, October). Computational Studies of RNA. Wayne State University, Detroit, MI.


Conference Presentations/Papers

Showing first 5 of 6.
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Zachary J. Fallon, Bernard, S.M.; Hoffman, M.T.; Hodges, W.T.; Miller III, Bill; Michael, L.A. and Nagan, M.C.* (2015). Molecular dynamics studies of retroviral arginine-rich peptide-RNA recogntion. In American Chemical Society. Boston, MA.

Stephen Telehany* and Nagan, Maria C. (2015). A Thermodynamic Study of 3’ Overhangs in the RNAi Mechanism. In Mercury Conference. http://mercuryconsortium.org/ Bucknell University, Lewisburg, PA.

Zachary J. Fallon* and Nagan, M.C. (2015). Characterization of Arginine-Rich Binding in Protein-RNA Interactions. In Mercury Conference. http://mercuryconsortium.org/ Bucknell University, Lewisburg, PA.

Zachary J. Fallon, Bernard, S.M.; Hodges, W.T.; Hoffman, M.T. and Nagan, M.C.* (2015). Molecular Dynamics Studies of HTLV-1 Rex Responsive Element Aptamer Recognition. In Albany 2015: The 19th Conversation. SUNY-Albany, Albany, NY.

Maia A. Jones* and Nagan, M.C. (2015). Molecular Dynamics Studies of HLTV-1 Rex-Rex Responsive Element Aptamer Recognition. In 17th Annual STEP Statewide Student Conference. Albany, NY.

Nagan, M.C.* (2011). The Role of Water, Dynamics and Quantum Stabilization in tRNA Structure. In RNA Dynamics Workshop. Telluride Science Research Center, Telluride, CO.


Honors and Accomplishments

2013 McNair Mentor Hall of Fame
2011 Sigma Xi, Kirksville Chapter - Researcher of the Year
2010 Walker and Doris Allen Fellowship for Faculty Excellence

Professional Activities

American Chemical Society, COMP Programming Board
Council on Undergraduate Research, Member