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Diplomas / Degrees

Ph. D., Rensselaer Polytechnic Institute (2007)
B.S., Rensselaer Polytechnic Institute (2003)

Recent Courses

Advanced Organic Chemistry Lecture
Organic Chemistry I
Organic Chemistry I Lab
Organic Chemistry II
Physiological Chemistry Rec

Teaching Specializations / Interests

Organic, Medicinal and Biochemistry

Research Interests

Fluorometric high-throughput screening (HTS) assays for cytochrome P450s (CYPs)

Recent Articles

Wentland, M.P., Lou, R., Lu, Q., Bu, Y., Denhardt, C., Jin, J., Ganorkar, R., VanAlstine, M.A., Guo, C., Cohen, D.J., Bidlack, J.M. (2009, 4). Syntheses of novel high affinity ligands for opioid receptors. BMCL, 19, 2289--2294

Wentland, M. P., Lou, R., Lu, Q., Bu, Y., VanAlstine, M.A., Cohen, D. J., Bidlack, J.M. (2009, 1). Syntheses and opioid receptor binding properties of carboxamido-substituted opioids. BMCL, 19, 203-208

VanAlstine, M. A.; Wentland, M. P.; Cohen, D. J.; Bidlack, J. M. (2007, 12). Redefining the structure-activity relationships of 2,6-methano-3-benzazocines. 5. Opioid receptor binding properties of N-((4��-phenyl)-phenethyl) analogues of 8-CAC. BMCL, 17, 6516-6520

Wentland, M. P.; VanAlstine, M. A.; Kucejko, R.; Lou, R.; Cohen, D. J.; Parkhill, A. L.; Bidlack, J. M. (2006, 8). Redefining the Structure-Activity Relationships of 2,6-Methano-3-benzazocines. 4. Opioid Receptor Binding Properties of 8-[N-(4'-phenyl)-phenethyl) carboxamido] Analogues of Cyclazocine and Ethylketocycalzocine. J. Med. Chem, 49, 5635-5639

Lou, R.; VanAlstine, M.; Sun, X.; Wentland, M. P. (2003, 2). Preparation of N-hydroxy succinimido esters via palladium-catalyzed carbonylation of aryl triflates and halides. Tetrahedron Letters, 44, 2477-2480

Conference Presentations and Papers

� VanAlstine, M. A., Hough, L.B (18 August 2009). Rat CYP2B1, CYP2C6 and CYP2C11: Optimization of fluorometric high throughput screens and epoxygenase inhibitor profiles . 236th ACS National Meeting, Philadelphia, PA

� J. L. Conroy, J.L., Nalwalk, J., VanAlstine, M.A., Knapp, B.I., Bidlack, J.M., Zuiderveld, O.P., Leurs, R., Shan, Z., Zhang, S., Wentland, M.P. and Hough, L.B., (24 July 2009). Blockade of morphine antinociception by inhibitors of cytochrome P450 and arachidonate epoxygenase. Soc. Neurosci. , San Diego, CA

� VanAlstine, M. A., Hough, L.B. (07 July 2009). Optimization Of A Fluorometric High Throughput Screen For Rat CYP2B1 And Its Inhibition By Imidazole-Containing Compounds. 17th International Symposium on Microsomes and Drug Oxidations, Saratoga Springs, NY

� Wentland, M. P.; Lou, R.; VanAlstine, M. A.; Sun, X.; Lu, Q.; Bu, Y.; Bidlack, J. M. (16 June 2009). Synthesis of carboxamido-containing opiates via N-hydroxysuccinimido activated esters. . 31st Northeast Regional Meeting of the American Chemical Society, Saratoga Springs, NY

� VanAlstine, M. A.; Wentland, M. P.; Kucejko, R. J.; Lou, R.; Cohen, D.; Knapp, B. I.; Bidlack, J. M. (27 March 2009). Synthesis and Evaluation of Novel N-substituted Derivatives of 8-Carboxamidocyclazocine. 231th ACS National Meeting, Atlanta, GA

Honors and Accomplishments

NIH Post-doctoral Fellow, Albany Medical College 2007-2009
John and Mary Cloke Prize, Rensselaer Polytechnic Institute, 2003
The Arthur G. Schultz Award for Undergraduate Research in Organic Chemistry, 2001

Professional Activities

American Chemical Society