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Diplomas / Degrees

Ph.D, Albert Einstein College of Medicine (Yeshiva University) (1999)
B.S., State University of New York at Stony Brook (1987)

Recent Courses

Biological Concepts And Methods 1 ( Lab )
Cell Biology
Cell Biology ( Lab )
Cell Biology ( Lecture )
Cell Biology Laboratory
Directed Readings Cancer Genetics
Directed Readings Cell Biology
Directed Readings Genetics Of Melanoma
Directed Readings Vhl Biology
Directed Readings Von Hippel-Lindau
Directed Work Experience Aquarium Internship
Graduate Genetics
Graduate Genetics Lab
Graduate Genetics Laboratory
Guided Research Cancer Research
Guided Research Vhl Cancer Research
Guided Research: Capstone Cancer Research
Guided Research: Capstone Experience - Cancer Research
Guided Research: Capstone Experience - Vhl Cancer Research
Scholarly Paper Brca1 Model Systems
Scientific Computer Graphics
Special Research Problems Vhl Cancer Research
Thesis Research Cellular Cancer Genetics
Thesis Research Vhl Cancer Research

Teaching Specializations / Interests

Genetics, cell biology, molecular biology, cancer biology

Research Interests

Cancer genetics and tumor suppressor genes: specifically, the normal cellular functions of the BRCA2 and VHL tumor suppressor genes.

For more information, please visit http://home.adelphi.edu/~sc17039/

Grants / Sponsored Research

National Institutes of Health Academic Research Enhancement Award (AREA) grant (2006-2009) to investigate the mechanisms responsible for tumors that are caused by mutations in a familial cancer gene (the von Hippel-Lindau tumor suppressor gene).

Other Scholarly / Artistic Work

Bangiyeva, V., Rosenbloom, A., Alexander, A.E., Isanova, B., Popko, T., and Schoenfeld, A.R. (2009). Differences in regulation of tight junctions and cell morphology between VHL mutations from disease subtypes. BMC Cancer 2009, 9(1):229. http://www.biomedcentral.com/1471-2407/9/229

Tannenbaum B., Mofunanya T., Schoenfeld A.R. (2007). DNA damage repair is unaffected by mimicked heterozygous levels of BRCA2 in HT-29 cells. Int. J. Biol. Sci. 3, 402-407. http://www.biolsci.org/v03p0402.htm

Hughes, M.D., Kapllani, E., Alexander, A.E., Burk, R.D., and Schoenfeld, A.R. (2007). HIF-2alpha downregulation in the absence of functional VHL is not sufficient for renal cell differentiation. Cancer Cell Int. 7:13. http://www.cancerci.com/content/7/1/13

Schoenfeld, A.R., Apgar, S., Dolios, G., Wang, R., and Aaronson, S.A. (2004). BRCA2 is ubiquitinated in vivo and interacts with USP11, a deubiquitinating enzyme that exhibits prosurvival function in the cellular response to DNA damage. Mol. Cell. Biol. 24, 7444-7455.

Schoenfeld, A.R., Davidowitz, E.J., and Burk, R.D. (2001). Endoplasmic reticulum/cytosolic localization of von Hippel-Lindau (VHL) gene products is mediated by a 64 amino acid region. Int. J. Cancer 91, 457-467.

Devarajan, P., DeLeon, M., Talasazan, F., Schoenfeld, A.R., Davidowitz, E.J., and Burk, R.D. (2001). The von Hippel-Lindau gene product inhibits renal cell apoptosis via Bcl-2-dependent pathways. J. Biol. Chem. 276, 40599-40605.

Davidowitz, E.J., Schoenfeld, A.R., and Burk, R.D. (2001). VHL induces renal cell differentiation and growth arrest through integration of cell-cell and cell-extracellular matrix signaling. Mol. Cell. Biol. 21, 865-874.

Schoenfeld, A.R., Davidowitz, E.J., and Burk, R.D. (2000). Elongin BC complex prevents degradation of von Hippel-Lindau tumor suppressor gene products. Proc. Natl. Acad. Sci. USA 97, 8507-8512.

Schoenfeld, A.R., Parris T., Eisenberger A., Davidowitz E.J., De Leon M., Talasazan F., Devarajan P., and Burk, R.D. (2000). The von Hippel-Lindau tumor suppressor gene protects cells from UV-mediated apoptosis. Oncogene 19, 5851-5857.

Schoenfeld, A., Davidowitz, E.J., and Burk, R.D (1998). A second major native von Hippel-Lindau gene product, initiated from an internal translation start site, functions as a tumor suppressor. Proc. Natl. Acad. Sci. USA 95, 8817-8822.

Bai, S., Schoenfeld, A., Pietrangelo , A., and Burk, R.D. (1995). Basal promoter of the rat connexin 32 gene: identification and characterization of an essential element and its DNA-binding protein. Mol. Cell. Biol. 15, 1439-1445.