Science Building Room 217
Science Building Room 217
Ph.D, MIT (1989)
B.A., Yale University (1983)
I served in the University's administration as associate provost from 2011 to 2016, and returned to the Biology Dept. in fall 2016. In the past I have taught introductory biology (Bio 111), genetics, cell biology I and II (capstone), genetics project lab, graduate genetics and lab, graduate developmental biology, and courses in science and society. My research interests are in plant molecular genetics.
Biological Concepts And Methods 1 ( Lab )
Genetics Project Lab
Guided Research Study Of Cytokinins
S/T: Stem Cells And Dna Editing
Senior Seminar: Topics In Biology-Capstone
Science and society
Plant molecular genetics: specifically, the molecular mechanism of action and of transport of the plant hormone auxin, and the role of auxin in plant physiology and development.
Hobbie, L.J. (2006), Auxin and cell polarity: the emergence of AXR4. Trends in Plant Science, 11, 517-518.
Hobbie L. (2005), Seek and ye shall [eventually] find: the end of the search for the auxin receptor. Journal of Integrative Plant Biology, 47, 1412-1417.
Dharmasiri N., Dharmasiri S., Weijers D., Lechner E., Yamada M., Hobbie L., Ehrismann J., Jurgens G., and Estelle M (2005), Plant development is regulated by a family of auxin receptor F box proteins. Developmental Cell, 9, 109-119.
Ren C., Pan J., Peng W., Genschik P., Hobbie L., Hellmann H., Estelle M., Gao B., Peng J., Sun C., and Xie D. (2005), Point mutations in Arabidopsis Cullin1 reveal its essential role in jasmonate response. Plant Journal, 42, 514-524.
Yang X., Lee S., So JH., Dharmasiri S., Dharmasiri N., Ge L., Jensen C., Hangarter R., Hobbie L., and Estelle M. (2004), The IAA1 protein is encoded by AXR5 and is a substrate of SCFTIR1. Plant Journal, 40, 772-782.
Ni W., Xie D., Hobbie L., Feng B., Zhao D., Akkara J., and Ma H. (2004), Regulation of flower development in Arabidopsis by SCF complexes. Plant Physiology, 134, 1574-1585.
Hellmann, H., Hobbie, L.J., Chapman, A., Dharmasiri, S., Dharmasiri, N., del Pozo, C., Reinhard, D., and Estelle, M. (2003), Arabidopsis AXR6 encodes CUL1 implicating SCF E3 ligases in auxin regulation of embryogenesis. EMBO Journal, 22, 3314-3325.
Hobbie, L.J. (2003), Auxin. Encyclopedia of Hormones, Academic Press.
Hobbie, L.J., McGovern, M., Hurwitz, L.R., Pierro, A., Liu, N.Y., Bandyopadhyay, A., and Estelle, M. (2000), The axr6 mutants of Arabidopsis define an essential gene involved in auxin response and early development. Development, 127, 23-32.
Gray, W.M., del Pozo, J.C., Walker, L., Hobbie, L., Risseeuw, E., Banks, T., Crosby, W.L., Yang, M., Ma, H., and Estelle, M. (1999), Identification of an SCF ubiquitin-ligase complex required for auxin response in Arabidopsis thaliana. Genes and Development, 13, 1678-1691.
Ruegger, M., Dewey, E., Gray, W.M., Hobbie, L., Turner, J., and Estelle, M. (1998), The TIR1 protein of Arabidopsis functions in auxin response and is related to human SKP2 and yeast Grr1p. Genes & Development, 12, 198-207.
Hobbie, L.J. (1998), Auxin: Molecular genetic approaches in Arabidopsis. Plant Physiology & Biochemistry, 36, 91-102.
Ruegger, M., Dewey, E., Hobbie, L., Brown, D., Bernasconi, P., Turner, J., Muday, G., and Estelle, M. (1997), Reduced NPA-binding in the tir3 mutant of Arabidopsis is associated with a reduction in polar auxin transport and diverse morphological effects. Plant Cell, 9, 745-757.
Hobbie, L., and Estelle, M. (1995), The axr4 auxin-resistant mutants of Arabidopsis define a gene important for root gravitropism and lateral root initiation. Plant Journal, 7, 211-220.
National Science Foundation grant, 2005-2009, $350,000, to use genetic approaches to analyze the function of the AUXIN-RESISTANT4 gene in membrane trafficking in the plant Arabidopsis thaliana.
National Science Foundation grant, $200,000,1996-1999, to characterize the auxin-resistant6 mutant of Arabidopsis thaliana.
2003: Fulbright Senior Scholar award, 5 months: to support sabbatical research in the Institute for Plant Sciences, Gif-sur-Yvette, France.
National Science Foundation grant,$225,000, 2000-2004, to identify and characterize the AUXIN-RESISTANT6 gene.
National Science Foundation grant, $19,000, 2002-2005, to implement a project-based laboratory for undergraduate genetics.
Selected as "Science Teacher of the Year" by Adelphi University chapter of AED/BBB (Premedical/Biology honor societies), 1997, 2002, 2004, 2005, 2011.
Winner of "Teaching Excellence Award" in the tenured faculty category, Adelphi University, 2008.
Reviewer of manuscripts for the journals Development, Plant Physiology, Plant Journal, Plant Cell, Plant Molecular Biology, and Nature Cell Biology.
Ad hoc grant reviewer for National Science Foundation and US Dept. of Agriculture
Instructor, Cold Spring Harbor Laboratory course in "Advanced Techniques in Plant Science", summers 2004, 2005, 2006
Member, grant review panels for National Institutes of Health (1998), National Science Foundation (2004, 2005), and US Dept. of Agriculture (2007, 2008).